Evolution. Directed.
On January 17th, 2022, Dr. Dorrazehi became the newest member of our team to successfully defend his PhD thesis. His thesis title is “The catalytic activity of a DD-peptidase impairs its evolutionary conversion into a β-lactamase“, which is focused on
Congratulation to Dr. Jason Chirakadavil! On August the 30th, he successfuly defended in front of a mixed remote and on-site audience. His thesis, “Deep mutational scanning of an alanine racemase from Streptococcus thermophilus” use the natural competence of Streptococcus bacteria
A lot of the work we do in the laboratory is trying to find better ways to do Directed Evolution. One of the thing we believe is that expressing libraries in their native genomic context let you navigate the fitness
The talented Emilie Gobbo took live sketchnote of Sebastian’s presentation for the MT180 contest. You can discover the result above. You can find the rest of Emilie’s work on facebook and instagram.
Sebastian joined the “Ma Thèse en 180 secondes“, the french version of the 3 minute thesis scientific vulgarization contest. We’re proud to announce that he was selected to represent the UCLouvain at the belgian final that will take place on
Preferences of DNA binding proteins for DNA Shape Beyond Sequence Motifs– Jason Baby Chirakadavil A graphical summary of the key points discussed in [1] Brief: Building on the recent line of research that DNA shape encodes specificity signals for transcription
In 1966, Lynn Margulis published her famous paper “On the origin of mitosing cells”. Bringing the theory of the endosymbiotic origin of organelles to the scientific community. Advance in molecular biology in the 1970’s brought evidence and the fact that
Discussion on Molecular Causes of Evolvability An interesting review on “The causes of evolvability and their evolution”, published by Payne and Wanger (2018), is discussed. Three major categories on the research of evolvability are discussed: phenotypic heterogeneity, mutational robustness and
Both our master students, Steve and Mathieu, are currently in Boston for the 2018 iGEM Jamboree, to present this year’s project, Bactwars, a new hope to fight pathogenic bacterias!