Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
2 credits
20.0 h
Q1
Teacher(s)
De Smet Charles; Demoulin Jean Baptiste (coordinator); Havelange Violaine;
Language
French
Prerequisites
Before taking this class, students must have followed molecular biology and genetic courses.
Main themes
- Cancer genetics: the goal of this chapter is to give an overview of the mechanism whereby the accumulation of DNA alteration give rise to cancer cells. We will define cancer cell clonality, oncogenes, tumor suppressors and cell selection and give specific examples.
- Cancer epigenetics: this chapter focuses on the epigenetic alterations of cancer cells, including challenges and therapeutic opportunities.
- Cancer genomics: this chapter focuses on novel technologies to study and diagnose cancer, in particular genome and transcriptome sequencing.
Aims
At the end of this learning unit, the student is able to : | |
| 1 |
After this course, students should: - Understand the genetic and epigenetic mechanisms of tumorigenesis. - Know the various types of DNA alterations and the methods that are available to study them. - Link cancer genetics with diagnosis, prognosis and treatment. Understand scientific literature on this topic (books, articles, publications, methods) |
The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Bibliography
"The biology of Cancer", 2d edition, Robert Weinberg, Ed Garland Science.
Faculty or entity
FASB
