Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
3 credits
30.0 h
Q2
Teacher(s)
Collet Jean-François; Lemaigre Frédéric (coordinator);
Language
French
Prerequisites
The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Content
The course complements and is an immediate extension of the Metabolic Biochemistry course WMDS1215 taught in the 1st quarter. The chapters include a description of normal biochemical mechanisms, as well as illustrations of disorders that cause human pathologies. More specifically, the following topics will be addressed:
Reminder of the mechanisms controlling gene expression
Diseases resulting from a dysfunction in gene expression
Oncogenes and tumor suppressors; dysfunction of signalling pathways in cancer
Normal and pathological metabolism of iron
Normal and pathological metabolism of heme
Biochemical mechanisms of blood coagulation
Lipoprotein metabolism
Metabolism of purines and pyrimidines
Amino acid metabolism.
Reminder of the mechanisms controlling gene expression
Diseases resulting from a dysfunction in gene expression
Oncogenes and tumor suppressors; dysfunction of signalling pathways in cancer
Normal and pathological metabolism of iron
Normal and pathological metabolism of heme
Biochemical mechanisms of blood coagulation
Lipoprotein metabolism
Metabolism of purines and pyrimidines
Amino acid metabolism.
Teaching methods
The teaching method consists of a lecture given in an auditorium by the different co-teachers, including many examples and illustrations.
Evaluation methods
The written examination will consist of open-ended question . Students will be evaluated on their ability to synthesize and integrate multiple biochemistry data into a coherent synthesis. They must be able to describe, use and explain in precise biochemical terms the topics addressed and how a disease can result from molecular and biochemical dysfunctions.
Online resources
The slides presented during the course, which cover the subject in a comprehensive way, are available on http://moodleucl.uclouvain.be/
Bibliography
Support: Manuels de biochimie. Références: - Biochemistry, Champe P.C., Harvey R.A, Ferrier D.R., Lippincott's Illustrated Reviews, Lippincott Williams & Wilkins - Principles of Biochemistry, Horton R.H., Prentice Hall
Textbook of Biochemistry with Clinical Correlations, 7ème édition, Thomas M. Devlin, Wiley
Textbook of Biochemistry with Clinical Correlations, 7ème édition, Thomas M. Devlin, Wiley
Teaching materials
- .
Faculty or entity
MED
Programmes / formations proposant cette unité d'enseignement (UE)
Title of the programme
Sigle
Credits
Prerequisites
Aims
Bachelor in Biomedicine
3
