Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
3 credits
30.0 h
Q1
Teacher(s)
Bommer Guido; Collet Jean-François; Lemaigre Frédéric (coordinator); Rider Mark;
Language
French
Prerequisites
The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Content
The course presents the basic principles of biochemistry as well as a series of human biochemistry themes considered as relevant to the training of students in Dentistry. The chapters on human biochemistry include a description of normal biochemical mechanisms, as well as illustrations of disorders that cause human pathologies. More specifically, the following topics will be addressed:
Reminder of the principles of thermodynamics
Structure and function of hemoglobin
Introduction to enzymes
Principles of enzyme kinetics
Principles of metabolic control
The glycolytic pathway and glycogen metabolism
The tricarboxylate cycle (Krebs cycle)
Amino acid metabolism
Fatty acid metabolism
Bile biochemistry (bilirubin, bile salts)
Mechanisms of gene expression and diseases related to gene dysfunctions
Reminder of the principles of thermodynamics
Structure and function of hemoglobin
Introduction to enzymes
Principles of enzyme kinetics
Principles of metabolic control
The glycolytic pathway and glycogen metabolism
The tricarboxylate cycle (Krebs cycle)
Amino acid metabolism
Fatty acid metabolism
Bile biochemistry (bilirubin, bile salts)
Mechanisms of gene expression and diseases related to gene dysfunctions
Teaching methods
Lectures
Evaluation methods
The written examination will consist in part of a multiple-choice questions and in part open-ended questions. Students will be evaluated on their ability to synthesize and integrate several biochemistry data into a coherent synthesis. They must be able to describe, use and explain in precise biochemical terms the topics addressed and how a disease can result from molecular and biochemical dysfunctions.
There are no negative points or weighting according to the questions and chapters of the subject. However, when a student has a final mark between 9/20 and 10/20 after correction, the lecturers review together the exam copy to decide whether the mark should be rounded down or up. It is therefore a complete re-evaluation of the copy that the 4 lecturers carry out. If the conclusion is that the answers are insufficient, the score will be rounded down.
There are no negative points or weighting according to the questions and chapters of the subject. However, when a student has a final mark between 9/20 and 10/20 after correction, the lecturers review together the exam copy to decide whether the mark should be rounded down or up. It is therefore a complete re-evaluation of the copy that the 4 lecturers carry out. If the conclusion is that the answers are insufficient, the score will be rounded down.
Online resources
The slides presented in the course, which cover the subject in a comprehensive way, are available on MoodleUCL (https://moodleucl.uclouvain.be/).
In addition, a tablet will be used to explain certain aspects of the course. The "Tablet" versions of the PowerPoint files will also be made available to students via MoodleUCL.
In addition, a tablet will be used to explain certain aspects of the course. The "Tablet" versions of the PowerPoint files will also be made available to students via MoodleUCL.
Bibliography
PC Champe & RA Harvey: Biochemistry. Lippincott Williams & Wilkins
Voet et Voet "Biochimie" 2e édition 2007, traduction de la 3e édition américaine par Guy Rousseau et Lionel Domenjoud
Textbook of Biochemistry with Clinical Correlations, 7ème édition, Thomas M. Devlin
Voet et Voet "Biochimie" 2e édition 2007, traduction de la 3e édition américaine par Guy Rousseau et Lionel Domenjoud
Textbook of Biochemistry with Clinical Correlations, 7ème édition, Thomas M. Devlin
Faculty or entity
MDEN
