Teacher(s)

Bertrand Luc coordinator; Bommer Guido; Collet Jean-François; Demoulin Jean Baptiste; Rider Mark;

Language

French

Prerequisites

Sbim2115 is a prerequisite

Main themes

This course helps to deepen the knowledge on post-translational modifications of proteins. It is the perfect continuation of wsbim2115.

Content

General introduction on the importance of post-translational modifications of proteins in their regulation and function (1h L.Bertrand)
-       Mechanisms of disulfide bond formation in prokaryotes and eukaryotes (3h J.-F. Collet)
-   Protein phosphorylations (4h M. Rider) 
- The new world of other post-translational modifications (Acetylation, O-GlcNacylation) (4h L. Bertrand)
-       Mechanisms of targeted proteolysis, protein ubiquitination and related post-translational modifications (J.B. Demoulin)
-       Protein and metabolite repair mechanisms. (G. Bommer)

Teaching methods

The different parts of the course will be given by specialists of the domains using powerpoint slides. The slides will be available for the students.

Evaluation methods

Written exam on all parts of the course

Bibliography

• Dias disponibles sur Moodle

Teaching materials

• Dias disponibles sur Moodle

Faculty or entity

SBIM