3.0 credits
20.0 h + 10.0 h
2q
Teacher(s)
Wallemacq Pierre ;
Language
Français
Main themes
Analytical methods used in clinical toxicology
Biological matrices
Toxicokinetics
Major intoxications (alcohols, CO, psychotropic drugs, drugs of abuse, sedatives
)
Pesticides
Mushrooms
Aims
This lecture aims to provide students the necessary understanding of the analytical, kinetics, and metabolic basis of the major intoxications found in clinical setting. At the end of this lecture, students should be able to discriminate potentially lethal intoxications, to propose analytical tools to detect toxics in biological fluids and to interpret analytical results in a medical context. The 10h of practical exercises are only proposed to specialized pharmacists in training in clinical biology (Master complementary)
The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Content
This lecture starts by a detailed review of the analytical methods available in clinical toxicology (immunoassays, chromatography including mass-spectrometric detection,
), together with basis of toxicokinetics. Major families of toxics are reviewed, and include solvants, CO, drugs of abuse, psychotropes, antidepressive drugs, sedatives
with some epidemiological, analytical, metabolic and clinical interpretation approaches. Practical exercises are offered to specialized pharmacists in clinical biology.
Other information
Evaluation : written exam
Support : Slides on I-campus
Faculty or entity<
