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Résumé :
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Background: Foodborne infections represent a significant public health burden. Moreover, antimicrobial resistance (AMR ) in Salmonella and Campylobacter is a growing problem, which is linked to antimicrobial use in food animals. We aimed to get insight on the occurrence and AMR of Salmonella and Campylobacter isolated from humans with diarrhoea and broiler chicken in Uzbekistan, as such data can help inform national policymaking on food safety and AMR .Methods: We conducted a survey during January–May 2015. We included a total of 84 intestinal samples from healthy broiler chicken and 81 samples from human patients with acute diarrhoea.Results: Salmonella and Campylobacter were isolated from the diarrhoeal disease cases, and were the etiological agents in 27% and 9% of the cases, respectively. Of the broiler chicken samples, 30% were positive for Salmonella and 30% for Campylobacter. We observed a high level of multiresistance among the Salmonella isolates: 80% and 50% of isolates from broiler chicken and humans, respectively, were resistant to five or six antimicrobial classes. A large proportion of Campylobacter isolates from both humans and broiler chicken (71% and 92%, respectively) were resistant to fluoroquinolones. Antibiograms for the Campylobacter isolates from humans and broiler chicken showed comparable patterns.Conclusion: Both Salmonella and Campylobacter seem to be important causes of diarrhoeal disease among humans in Uzbekistan, and broiler chicken seems to be a contributing source of infection. The level of AMR seems high among Campylobacter and Salmonella from both broiler chicken and humans, which may partly reflect the use of antimicrobial agents in the poultry industry in Uzbekistan
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