Titre :
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Environmental cadmium exposure and osteoporosis : a review (2013)
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Auteurs :
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JAMES K.
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Type de document :
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Article : texte imprimé
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Dans :
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International Journal of Public Health (Vol. 58 n° 5, Octobre 2013)
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Article en page(s) :
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pp.737–745
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Note générale :
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biblio.
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Langues:
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Anglais
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Catégories :
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REVUE DE LITTERATURE
OSTEOPOROSE
ENVIRONNEMENT
POLLUTION
ECOLOGIE
CHIMIE
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Mots-clés:
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REVUE DE LITTERATURE
;
OSTEOPOROSE
;
ENVIRONNEMENT
;
POLLUTION
;
ECOLOGIE
;
CHIMIE
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Résumé :
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ObjectivesTo review the published literature investigating the association between cadmium exposure and osteoporosis.MethodsA review of published peer-reviewed literature based on a priori criteria was completed. Odds ratios (OR) were abstracted or estimated from observational studies to calculate a pooled OR using inverse variance weighted random effects models.ResultsThe review identified seven studies with a pooled OR of OR = 2.22 (95 % CI: 1.16, 4.28) [I2 = 54.8 % (p < 0.05)] (comparing highest urine cadmium category to lowest). In women over the age of 50 years, the pooled OR was 1.82 (95 % CI: 1.63, 2.02) [I2 = 73.1 % (p < 0.05)]. A dose response evaluation (six studies) suggested increasing odds for osteoporosis with increasing urine cadmium levels.ConclusionsThis review detected an association between cadmium exposure and the occurrence of osteoporosis in a small number of cross-sectional studies which requires confirmation in using prospective study design.
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Note de contenu :
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SCIENTIFIQUE
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