![The Impact of Health Promotion Interventions on Telomere Length: A Systematic Review](./styles/zen/images/no_image.jpg)
Titre : | The Impact of Health Promotion Interventions on Telomere Length: A Systematic Review (2020) |
Auteurs : | Chan Qiao, Auteur |
Type de document : | Article : texte imprimé |
Dans : | American Journal of Health Promotion (vol. 34, n°6, Juillet 2020) |
Article en page(s) : | pp. 633–647 |
Langues: | Anglais |
Catégories : | |
Résumé : |
Objectives:
The aim of this study was to evaluate the effectiveness of health promotion interventions in delaying telomere shortening (a biomarker for aging). Data Source: PubMed, PsychINFO, EMBASE, CINAHL, and Cochrane Library databases. Study Inclusion and Exclusion Criteria: Inclusion criteria: (1) empirical studies involving human subjects; (2) health promotion intervention studies including both randomized control trials (RCTs) and non-RCTs.; (3) measured telomere length as an intervention outcome; and (4) were written in English. Exclusion criteria: (1) observational studies without any health promotion intervention practices and (2) did not report intervention effects. Data Extraction: Data extraction was performed by two reviewers following the preferred reporting items for systematic reviews and meta-analysis guidelines. Data Synthesis: Substantial heterogeneity in intervention type and study design in the included studies precluded a meta-analysis. We conducted a narrative synthesis instead. Results: Thirty studies were included in the review, of which 16 were RCTs. One-third of the included studies reported significant intervention impacts in delaying telomere shortening, with relatively consistent significant results emerged from weight-loss interventions and interventions involving multiple lifestyle modification components (eg, diet and exercise). Most of supplement intervention studies observed null effects in telomere length. Conclusions: Weight-loss and comprehensive lifestyle intervention strategies show encouraging impacts in delaying telomere shortening. More rigorous studies targeting populations at different age stages through life span are needed. |
Catalogueur : | RESOdoc |
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Cote | Code-barres | Support | Localisation | Disponibilité |
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RESO A.19 | RE65681827 | Bulletin | RESOdoc | Consultation sur place Disponible |