3.00 credits
30.0 h + 10.0 h
Q1
Teacher(s)
Demoustier Sophie; Dupont Christine;
Language
English
> French-friendly
> French-friendly
Prerequisites
Students need to master the following skills, basic concepts in general chemistry and chemical physics, organic chemistry and biochemistry, and biology and cellular physiology taught during the Bachelor's degree (e.g. in the following courses : LFSAB1301 or LCHM1111, LBIR1220A, and LGBIO1111 or LBIR1150)
Main themes
General introduction to main classes of biomaterials: structure of natural and synthetic materials (polymers, ceramics and glasses, metals and composites).
Properties of biomaterials: mechanical properties, surface vs bulk properties, physical and chemical properties, degradability, etc. This includes the study of living organism-material interactions: protein adsorption, cell adhesion, inflammatory and immune reactions, coagulation, etc.
Examples of application of different classes of biomaterials in medicine: cardiovascular and orthopedic devices, dental materials, tissue engineering, etc.
Properties of biomaterials: mechanical properties, surface vs bulk properties, physical and chemical properties, degradability, etc. This includes the study of living organism-material interactions: protein adsorption, cell adhesion, inflammatory and immune reactions, coagulation, etc.
Examples of application of different classes of biomaterials in medicine: cardiovascular and orthopedic devices, dental materials, tissue engineering, etc.
Content
Part 1 : General introduction to main classes of biomaterials
- 1.1 Polymers
- 1.2 Metals
- 1.3 Ceramics
- 1.4 Compositifs
- 1.5 Hydrogels
- 1.6 Natural Materials
- 2.1 Mechanicals properties
- 2.2 Surface vs bulk properties
- 2.3 Living organism-biomaterial interactions
Teaching methods
The first part of the teaching unit consists in lectures covering three axes: (i) principles of biology related to host-biomaterial interactions; (ii) general introduction to main classes of biomaterials: structure of natural and synthetic materials (polymers, ceramics and glasses, metals and composites); (iii) properties of biomaterials: mechanical properties, physical and chemical properties, surface properties, and relation between these properties and host-material interactions. The lectures als includes a series of applications of different classes of biomaterials in medicine, biology and artificial organs. This part of the course could also be illustrated through presentations by experts from research and industry.
The second part of the teaching unit consists in a project, prepared by teams of four to five students. On the basis of scientific papers or book chapters, the students will discuss a current issue in biomaterials science. Regular mentoring session with the teachers are organized, to orient students in their search of appropriate literature, and to help them structuring and writing the report. At the end of the semester, the work is presented to the other students following the same teaching unit.
The second part of the teaching unit consists in a project, prepared by teams of four to five students. On the basis of scientific papers or book chapters, the students will discuss a current issue in biomaterials science. Regular mentoring session with the teachers are organized, to orient students in their search of appropriate literature, and to help them structuring and writing the report. At the end of the semester, the work is presented to the other students following the same teaching unit.
Evaluation methods
Final indivudual oral or written exam during the session (50 % of final grade). The exact modalities will be communicated at the latest in week 4 when the number of students attending the course will be known.
Project evaluation (50 % of final grade): the written report is taken into account, as well as the oral presentation in front of the students participating to the course. The mark attributed to the work done during the semester (that means, the mark attributed for the group project work) is acquired for all the sessions of the academic year, by virtue of the article 78 of the RGEE. Except exceptional situations, the evaluation takes the group performance into account and is identical across the group students. Individual students who would not have provided a fair personal contribution within their group will perform individual complementary work (to be determined) that will be evaluated within the exam session of September.
For students registered for a partim (LGBIO2030A, 3 ECTS), the final grade is solely based on the final examination.
Project evaluation (50 % of final grade): the written report is taken into account, as well as the oral presentation in front of the students participating to the course. The mark attributed to the work done during the semester (that means, the mark attributed for the group project work) is acquired for all the sessions of the academic year, by virtue of the article 78 of the RGEE. Except exceptional situations, the evaluation takes the group performance into account and is identical across the group students. Individual students who would not have provided a fair personal contribution within their group will perform individual complementary work (to be determined) that will be evaluated within the exam session of September.
For students registered for a partim (LGBIO2030A, 3 ECTS), the final grade is solely based on the final examination.
Other information
The course can be taken as a partim [LGBIO2030A] (3 ECTS, 30 h + 10 h). In such case, the student does not prepare a project, but participates to project presentation by other student.
Online resources
Bibliography
Livre de référence e-textbook :
Biomaterials Science – An Introduction to Materials in Medicine (Eds BD Ratner, AS Hoffman, JE Lemons, FJ Schoen,), third edition, Elsevier Academic Press, San Diego, 2012.
The full text book is available online on Ebook Central (when you are logged on the UCLouvain network)
Biomaterials Science – An Introduction to Materials in Medicine (Eds BD Ratner, AS Hoffman, JE Lemons, FJ Schoen,), third edition, Elsevier Academic Press, San Diego, 2012.
The full text book is available online on Ebook Central (when you are logged on the UCLouvain network)
Faculty or entity
GBIO
Programmes / formations proposant cette unité d'enseignement (UE)
Title of the programme
Sigle
Credits
Prerequisites
Learning outcomes
Master [120] in Chemistry and Bioindustries
