Due to the COVID-19 crisis, the information below is subject to change,
in particular that concerning the teaching mode (presential, distance or in a comodal or hybrid format).
3 credits
30.0 h
Q1
Teacher(s)
Batoko Henri; Hallet Bernard; Morsomme Pierre; Page Melissa (compensates Rezsohazy René); Rezsohazy René;
Language
English
Main themes
The main topics of the course include :- signalling modules and pathways involved in cell perception and communication- mechanisms of gene regulation including epigenetic modifications of DNA and chromatin, transcriptional and translational regulations (small RNAs etc
), as well as the posttranslational modifications of proteins and their turnover- regulation of metabolic activities- cell cycle and its control- molecular bases of cell differentiation and cell death- intracellular trafficking
Aims
At the end of this learning unit, the student is able to : | |
| 1 | The course aims at integrating the molecular and cellular bases of the living world, from prokaryotic to eukaryotic cells. It should be regarded as an in-depth continuation of the undergraduate foundations acquired through the relevant cell biology, molecular genetics, biochemistry and metabolism courses, with emphasis on the integration of approaches and methodologies underpinning our understandings of life. The purpose is to understand how a cell can perceive the variations of its environment (within an organism or as a population of cells) and how it will translate these environmental cues into an appropriate response. This will require the understanding of different modes of cell communication and pathways underlying information transduction as well as their outputs in terms of metabolic activity, gene expression, cell division or differentiation. The various aspects will be treated with an evolutionary perspective, highlighting the common themes of life as opposed to peculiarities of the microbial, plant or animal worlds.This course should be considered as an anchor for the more specialized studies in molecular and cellular biology of microorganisms, plants, animals and humans, within the master program. |
Content
The content of the course is divided into specific modules developed by each lecturer, making the best possible use of his/her main expertise and up-to-date literature in his/her field of interest. Each scientific concept is developed with the aim of highlighting the current state-of-the-art, both in terms of basic knowledge and technological approaches.
Teaching methods
Due to the COVID-19 crisis, the information in this section is particularly likely to change.
Ex cathedra presentations, four modules proposed by 4 different lecturers
Evaluation methods
Due to the COVID-19 crisis, the information in this section is particularly likely to change.
For each module, the analysis of a compulsory article is asked of the students, the evaluation consists of an open discussion with each lecturer about each of the imposed articles.Typically, this evaluation occurs over one day in the January exam session, however for 2020-2021 the students will be given the option to have the exams split between the normal semester and the exam session. This option will be discussed in the first lecture and the final decision is based on a majority decision.
Other information
Precursory courses: Students must be familiar with most fundamental concepts and techniques in molecular and cellular biology (level BIO13)
Online resources
The slides used for the ex cathedra courses (.ppt) are available via Moodle. The articles to be analyzed for evaluation are also posted on Moodle at the end of the presentations.
Teaching materials
- Documents et articles scientifiques proposés par les co-titulaires disponible sur moodle
Faculty or entity
BIOL
