Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
2 credits
15.0 h
Q2
Teacher(s)
Frédérick Raphaël (coordinator); Lambert Didier;
Language
French
Prerequisites
WFARM1231 chimie organique
L'unité d'enseignement suivante devra être acquise ou figurer dans le programme de l'étudiant la même année académique : WFARM1302 (chimie pharmaceutique).
The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
L'unité d'enseignement suivante devra être acquise ou figurer dans le programme de l'étudiant la même année académique : WFARM1302 (chimie pharmaceutique).
The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Main themes
This course offers aimed at deepening the concepts presented in the pharmaceutical chemistry course. The concepts of drug design are discussed through selected examples.
They include:
- the main pharmacomodulation concepts
- the rational approaches based on the knowledge of the structure of the target or of the ligands (X-ray, NMR, molecular modeling, pharmacophore approach) incorporating notions seen in the course of biophysics
They include:
- the main pharmacomodulation concepts
- the rational approaches based on the knowledge of the structure of the target or of the ligands (X-ray, NMR, molecular modeling, pharmacophore approach) incorporating notions seen in the course of biophysics
Aims
At the end of this learning unit, the student is able to : | |
| 1 |
The course aims at introducing students to the rational design of drugs ("drug design") by means of selected examples either through conventional pharmacochemical modulations or by means of rational approach based on the three-dimensional structure of the target. It also offers an introduction to molecular modeling (molecular dynamics molecular mechanics and semi-quantum methods) and methods of modern drug discovery using the use of bank products (combinatorial chemistry, high throughput screening, .. .). |
The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Faculty or entity
FARM
