Tissue Engineering

lgbio2071  2019-2020  Louvain-la-Neuve

Tissue Engineering
Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
5 credits
30.0 h + 30.0 h
Q2
Teacher(s)
Kerckhofs Greet;
Language
English
Prerequisites
Basic knowledge in biology, as treated in the course LGBIO1111 of the bachelor in civil engineering, and basic knowledge in anatomy and physiology of biological systems, as treated in the course LGBIO1113 of the bachelor in civil engineering, are required.
Main themes
The term 'tissue engineering' was officially coined at a National Science Foundation workshop in 1988 to mean 'the application of principles and methods of engineering and life sciences toward the fundamental understanding of structure-function relationships in normal and pathological tissues and the development of biological substitutes to restore, maintain or improve tissue function'.
During this course, the following basic principles of Tissue Engineering will be addressed for regeneration of different tissues (skin, bone, cartilage, etc.) :
* cell biology: stem cells, cell harvest, culture, extension and differentiation, '
* biomaterial science: general overview of the different classes of biomaterials, and their specific needs for tissue engineering purposes
* bioprocessing technology: bioreactors and bioprocessing, design of biologically effective, yet scalable, devices.
* in silico approaches: analytical and computational modeling for tissue engineering applications
* preclinical screening and clinical application: animal models, ethical considerations, upscaling, ....
Aims

At the end of this learning unit, the student is able to :

1 At the end of this course, students will be able to:
a. Disciplinary Learning Outcomes
  • Understand the interdisciplinary nature of Tissue Engineering and the need for a close collaboration between engineers, biologists and clinicians.
  • Describe the basic principles of Tissue Engineering, and understand how they interact with each other. This provides the students with the knowledge and vocabulary necessary for communication with biomedical experts and clinicians.
  • Evaluate and critically discuss scientific papers specifically related to Tissue Engineering.
b. Transversal Learning Outcomes
  • Search and read a scientific paper with regards to a specific basic principle of tissue engineering, and critically evaluate its main results.
  • Make a poster of this paper, and present this to your peers by clearly stating the context and providing a critical opinion about the topic.
 

The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Teaching methods
  • Theoretical lectures
  • Seminars by experts in the field and lab visit
  • Q&A sessions about the project
Evaluation methods
  • Closed-book written examination
  • Projects with written reports and poster
Online resources
Moodle
Faculty or entity
GBIO


Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Sigle
Credits
Prerequisites
Aims
Master [120] in Biomedical Engineering