Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
4 credits
30.0 h
Q1
Teacher(s)
Bertrand Luc; Cani Patrice (coordinator); Gilon Patrick; Horman Sandrine; Lanthier Nicolas; Veiga da Cunha Maria;
Language
French
Prerequisites
Bachelor in Biomedical Sciences or Pharmaceutical Sciences, Bachelor in Bioengineering
Main themes
This course aims to study the mechanisms involved in the regulation of cellular activity and metabolism. Different membrane and nuclear receptors as well as transcription factors directly regulated by nutrients and/or their metabolites will be investigated (e.g. : PPAR's, FXR, chREBP, GRP40/120/119/41/43, Toll like receptors (TLR's)). We will also study the mechanisms regulating specific signaling pathways involved in energy homeostasis, lipid and glucose metabolism (e.g., insulin, AMPK, mTOR, ROS).
Aims
At the end of this learning unit, the student is able to : | |
| 1 |
At the end of this course, the students will be able : (1) to understand and to explain the cellular and molecular mechanisms influenced by nutrients (e.g.: different type of lipids, proteins and amino acids, specific carbohydrates) and their cellular metabolites (e.g.: ceramides, DAG, endocannabinoids, ...), (2) to describe the mechanisms regulating gene expression directly connected with energy, glucose and lipid metabolism, (3) to understand the key features regulating physiology and metabolism and that may be involved in the onset of specific pathological disorders such as obesity, type 2 diabetes, metabolic inflammation, cardiovascular diseases, pancreatic and hepatic diseases. |
The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Teaching methods
The team of teacher is composed of professors that have a specific knowledge and complementary expertise in molecular and cellular aspects. Each member of the team will teach themes that are in his field of expertise and for some of them directly developed in their research practice. It is worth noting that this will be coordinated between the different members of the teaching team in order to integrate as much as possible all the different aspects of the course. Finally, this approach will help to maintain the content of the course relatively up to date in this fast moving field.
Evaluation methods
Written exam on all parts of the course. The student should provide criticism and integrate the different themes addressed during the course
Faculty or entity
FASB
