Biomaterials

lgbio2030a  2019-2020  Louvain-la-Neuve

Biomaterials
Note from June 29, 2020
Although we do not yet know how long the social distancing related to the Covid-19 pandemic will last, and regardless of the changes that had to be made in the evaluation of the June 2020 session in relation to what is provided for in this learning unit description, new learnig unit evaluation methods may still be adopted by the teachers; details of these methods have been - or will be - communicated to the students by the teachers, as soon as possible.
3 credits
30.0 h + 10.0 h
Q1
Teacher(s)
Demoustier Sophie; Dupont Christine;
Language
French
Prerequisites
Students need to master the following skills, basic concepts in general chemistry and chemical physics, organic chemistry and biochemistry, and biology and cellular physiology taught during the Bachelor's degree (e.g. in the following courses : LFSAB1301 or LCHM1111, LBIR1220A, and LGBIO1111 or LBIR1150)
Main themes
General introduction to main classes of biomaterials: structure of natural and synthetic materials (polymers, ceramics and glasses, metals and composites).
Properties of biomaterials: mechanical properties, surface vs bulk properties, physical and chemical properties, degradability, etc. This includes the study of living organism-material interactions: protein adsorption, cell adhesion, inflammatory and immune reactions, coagulation, etc.
Examples of application of different classes of biomaterials in medicine: cardiovascular and orthopedic devices, dental materials, tissue engineering, etc.
Content
Part 1 : General introduction to main classes of biomaterials
  • 1.1 Polymers
  • 1.2 Metals
  • 1.3 Ceramics
  • 1.4 Compositifs
  • 1.5 Hydrogels
  • 1.6 Natural Materials
Part 2 : Properties of biomaterials
  • 2.1 Mechanicals properties
  • 2.2 Surface vs bulk properties
  • 2.3 Living organism-biomaterial interactions
Part 3 : applications of biomaterials in medicine
Teaching methods
The first part of the teaching unit consists in lectures covering three axes: (i) principles of biology related to host-biomaterial interactions; (ii) general introduction to main classes of biomaterials: structure of natural and synthetic materials (polymers, ceramics and glasses, metals and composites); (iii) properties of biomaterials: mechanical properties, physical and chemical properties, surface properties, and relation between these properties and host-material interactions.
The second part  of the teaching unit includes a series of application of different classes of biomaterials in medicine, biology and artificial organs: biomaterials for cardiovascular applications, orthopedic prostheses, dental materials, drug delivery systems, biosensors, tissue engineering, etc. This part of the course is illustrated through presentations by experts from research and industry. Moreover, the visit of a company active in the field of biomaterials may be proposed.
The third part of the teaching unit consists in a project, prepared by teams of two to three students. On the basis of at least a dozen of scientific papers or book chapters, the students will discuss a current issue in biomaterials science. Regular mentoring session with the teachers are organized, to orient students in their search of appropriate literature, and to help them structuring and writing the report. At the end of the semester, the work is presented to the other students following the same teaching unit.
Evaluation methods
  • Final oral exam during the session (50 % of final grade)
  • Project evaluation (50 % of final grade): the written report is taken into account, as well as the oral presentation in front of the students participating to the course.
  • For students registered for a partim (LGBIO2030A, 3 ECTS), the final grade is solely based on the final examination.
Other information
The course can be taken as a partim [LGBIO2030A] (3 ECTS, 30 h + 10 h). In such case, the student does not prepare a project, but participates to project presentation by other student.
Bibliography
Livre de référence (exemplaires prêtés aux étudiants par groupe) :
Biomaterials : The intersection of Biology and Materials science : Int. Edition
J. Temenoff & A. Mikos, Pearson Education
Faculty or entity
GBIO


Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Sigle
Credits
Prerequisites
Aims
Master [120] in Chemistry and Bioindustries