At the end of this learning unit, the student is able to : | |
| 1 | At the end of the course, the student will be able : - to describe the processes that contribute to the formation of the structures of the central and peripheral nervous system, and to explain the developmental relationships between these structures - to understand and compare the regulatory mechanisms that are activated during development in different regions of the nervous system (organizing centres, control of neurogenesis, of neuronal differentiation and migration, of axonal growth, of synaptogenesis and of circuit formation) - to explain the mechanisms and the consequences of endogenous or exogenous alterations of these processes - to propose adequate experimental strategies to study specific aspects of neural development - to make anatomical and functional links between developing structures and structures of the adult nervous system The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled ¿Programmes/courses offering this Teaching Unit¿. |
The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
1. Neural induction and neurulation
2. Antero-posterior and dorso-ventral patterning of the nervous system
3. Neural stem cells and neurogenesis
4. Neuronal specification and differentiation
5. Neuronal migration
6. Neuronal survival and neuronal death
7. Neural crest cells
8. Axonal growth and guidance
9. Development of glial cells, myelinisation
10. Synaptogenesis and synaptic pruning
11. Neural circuit formation and activity-dependent maturation
12. Developmental alterations of the nervous system
13. Specific experimental approaches
The course will be given as a series of lectures including collective analysis of key research articles. Exercises based on in silico training or searches (expression databases, ') or laboratory demonstrations could be organized.
