Teacher(s)

Feron Olivier; Hermans Emmanuel coordinator; Mingeot Marie-Paule; Sonveaux Pierre;

Language

French

Prerequisites

Understanding the concepts developed in this course requires basic training in health sciences. This graduate course is therefore only accessible to students with a bachelor's degree in pharmaceutical, biomedical, medical or dental sciences, or who finalize such a bachelor's degree.

Main themes

Through the description of recent research, the functioning of certain receptors, certain enzymes, transporters are becoming better known. This makes it possible to better define their potentiality as drug targets. The course of molecular pharmacology gives the opportunity to deepen the exploration of molecular mechanisms that are involved in the responses to certain drugs. The course is structured around a few examples of pharmacological targets already exploited or not exploited to date, but promising for future developments. This is the case, for example, of membrane receptors and regulating intracellular proteins, conveyors or efflux pumps.

Aims

At the end of this learning unit, the student is able to :
1	The objective of the course is to train students to understand the complexity of molecular targets used in pharmacology. This complexity constitutes a wealth in the development of drugs with better selectivity and efficiency. The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled ¿Programmes/courses offering this Teaching Unit¿.

The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.

Content

The course is given in a small committee of about fifteen students and allows to engage in real discussions around new concepts inspired by recent publications. Even if the therapeutic effects are reflected at the level of the organ or the whole organism, the course focuses mainly on molecular mechanisms.

Evaluation methods

Written exam with questions of reflection (open question). No memorization, but understanding, critical thinking and an effort of synthesis.
 

Other information

Teaching schedule: 2-h modules attributed in part to teachers of Medicinal Chemistry, Pharmacology and/or Pharmacotherapy having interest and competencies for new drug development in respect to the compounds that will be addressed (independent experts could also be invited).

Bibliography

• pdf des slides du cours disponibles sur moodle

l'essentiel des documents présentés aux cours sont accessibles sur Internet via la plateforme Moodle accessible aux membres de la communauté universitaire.

Teaching materials

• pdf des slides du cours disponibles sur moodle

Faculty or entity

FARM