5 credits
30.0 h + 22.5 h
Q2
This biannual learning unit is not being organized in 2018-2019 !
Teacher(s)
Deleersnijder Eric coordinator; Hanert Emmanuel; Van Effelterre Thierry;
Language
English
Prerequisites
This course requires prior training in ordinary and partial differential equations (ODEs and PDEs).
Main themes
This course covers the mathematical modelling of ecological and epidemiological processes in the context of systems theory. It aims to analyse the properties of key ecological and epidemiological models, particularly population models. Basically, the models studied refer to the laws of physics, and in particular the concepts of conservation of matter. This course aims to introduce basic tools for understanding and, if possible predicting, the spatio-temporal evolution of ecological and epidemiological systems. These tools include ordinary differential equations, partial differential equations and numerical methods to approximate these equations.
Aims
At the end of this learning unit, the student is able to : | |
1 | Contribution of the course to the program objectives
Specific learning outcomes of the course At the end of the course LMAPR2510, students will be able to:
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The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Content
The course covers the following elements, in particular through a detailed presentation of examples made ''using Matlab:
- Single-species population models: logistic growth model - microbial growth models - age distribution models.
- Populations interactions and biodiversity models: predator-prey Lotka-Volterra models - competitive exclusion principle - coexistence.
- Key elements of mathematical modeling in epidemiology of infectious diseases: types of natural history of infections, types of transmission (e.g. direct contact or contact through a vector), socio-demographic aspects (e.g. contacts between individuals) - stratification of the population ' compartmental models ' dynamics at the population level (epidemics, endemic states) - basic reproduction ratio (R0) - infectious disease control - indirect protection - deterministic models (ODEs and PDEs) and stochastic models (Markov models, network model). Illustration by examples of different models addressing public-health issues: understanding the population dynamics, assessing of the potential impact of various interventions such as vaccinations, antibiotics/antivirals, behavioral changes (e.g. quarantine)
- Application of modeling to understanding the biology of infectious diseases in an individual: dynamics of immune cells and their interaction with a pathogen illustrated by simple models based on the mathematical immunology.
- Random walks, diffusion and characteristic time scales.
- Population dynamics in space : advection-diffusion-reaction equations - dynamics of a species in the presence of dispersion - dynamics of several species with dispersion - nonlinear progressive waves - effect of dispersion on populations in competition ' pattern formation.
Teaching methods
The course is taught through lectures that include many examples. Practicals and larger-scale individual projects are also proposed to the students so that they can implement the theoretical concepts covered in the lectures.
Evaluation methods
Individual report based on a project and oral defense during the exam session.
Other information
The notes are written in English. Lectures can be given in French or English according to the wishes of the students.
This course requires prior training in ordinary and partial differential equations (ODEs and PDEs).
This course requires prior training in ordinary and partial differential equations (ODEs and PDEs).
Online resources
Lecture notes and Matlab scripts available on Moodle :
https://moodleucl.uclouvain.be/course/view.php?id=9201
https://moodleucl.uclouvain.be/course/view.php?id=9201
Bibliography
- Supports de cours : Notes de cours et programmes Matlab disponibles sur iCampus.
- Ouvrages de référence : May R.M., 1973, Stability and Complexity in Model Ecosystems, Princeton University Press - Murray J.D., 2002 (3rd ed.), Mathematical Biology (Vol. I & II), Springer - Okubo A., 1980, Diffusion and Ecological Problems: Mathematical Models, Springer-Verlag - Keeling M.J. & Rohani P., 2007, Modeling Infectious Diseases in Humans and Animals, Princeton University Press - Brauer F., van den Driessche P. & Wu J., 2008, Mathematical Epidemiology, Springer.
Faculty or entity
MAP