30.0 h + 20.0 h
Elias Benjamin coordinator; Fustin Charles-André;
The goal of this course is not only to provide the basics of modern organic chemistry, but also to link them to certain fundamental concepts detailed in the general chemistry course (chemical bonding, thermodynamics, chemical kinetics, acid-base reactions). The first part of the course will essentially install the basic concepts by the description of the main classes of functional groups and the organic nomenclature. The physico-chemical properties as well as the electronic effects will be covered then applied to specific examples. The 3D structures of organic molecules, as well as the various isomerisation phenomena that result from it, will be detailed then applied to different examples linked to fundamental biological and biochemical processes. The introduction to chemical reactivity is centred on four main classes of organic functions : alkenes, halogenoalkanes, carbonyl derivatives (aldehydes and ketones) and carboxylic acids and their derivatives. This part leads to the introduction of new concepts, among which the notion of reactive intermediates: nucleophiles and electrophiles, the notion of reaction rate, selectivity in organic chemistry, interconversion between functional groups. In many cases, examples taken from biochemical mechanisms and linked to the field of life sciences will illustrate these concepts. Examples pertaining to daily life will also be used, including polymers and drugs. The theoretical course will be completed by exercice sessions and by a practical course which will familiarize the student with basic techniques such as distillation and chromatography, and teach him some experimental method.
Prerequisites: Secondary school level. Course of general chemistry bac11: CHM1111. Evaluation: theorical questions and practical exercises (exercises will be similar than those made during course and exercise sessions). Written examination with facultative oral questions. Support: book "Introduction à la chimie organique" by Hart/Conia (InterEditions).
- ' Chimie organique, P. Bruice (Pearson) ' Chimie organique simple et intuitive, D. Klein (deBoeck)
- – Chimie organique, P. Bruice (Pearson) – Chimie organique simple et intuitive, D. Klein (deBoeck)
Faculty or entity