Teacher(s)
Beauloye Christophe; Feron Olivier; Jonas Jean-Christophe coordinator; Kienlen-Campard Pascal; Pilette Charles;
Prerequisites
This course requires good knowledge of cellular and molecular biology, biochemistry of cell metabolism, immunology, cell and organ physiology, and human pathology.
Main themes
At the end of the year, the student will :
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know the pathophysiology of the diseases covered during classes, from the molecule to the cell, the cell to the organ, and the organ to the organism
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understand/be able to explain the link between the molecular and cellular alterations described and the development of the chronic diseases covered during classes, as well as the mode of action of drugs targeting these alterations and their impact in other organs
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be able to analyze and criticize a conference or paper in that field ; use his/her new knowledge and skills to investigate unaswered questions on the topic
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imagine new approaches to study the pathophysiology of other diseases
Aims
At the end of this learning unit, the student is able to : |
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At the end of the class, the student should:
(1) know the pathophysiology of diseases specifically addressed during the class, not only from the molecular and cellular point of view, but also in a larger perspective (organs, organism);
(2) understand and explain the link between the molecular and cellular dysfunction and disease development; understand and explain the mode of action of drugs targeting these alterations;
(3) be able to critically analyze a presentation or scientific paper about
the subject ; use her knowledge to address new questions in the field ;
(4) be able to propose experimental approaches to study the molecular and cellular pathophysiology of other diseases.
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The contribution of this Teaching Unit to the development and
command of the skills and learning outcomes of the programme(s) can be
accessed at the end of this sheet, in the section entitled
“Programmes/courses offering this Teaching Unit”.
Content
The classes will cover the pathophysiological mechanisms underlying the development of frequent non-communicable human diseases, the drugs targeting these mechanisms and unanswered questions on the topic (biomedical research). The link between the molecular, cellular, and tissue alterations and their impact on the whole organism will be highlighted as much as possible. Diseases covered during classes: diabetes and its complications ; cardiovascular diseases; respiratory diseases; neurodegenerative diseases ; cancers.
Evaluation methods
Written examination, unless specified otherwise by each professor. The final note may be lower than the arithmetic mean of the notes obtained in each part; penalties will be applied in case of a major failure in one part, whatever the note obtained for the other parts.
Other information
Slides projected during classes and additional documents will be posted on MoodleUCL.
