2 credits
20.0 h
Q1
Teacher(s)
Bertrand Luc coordinator; Collet Jean-François; Demoulin Jean Baptiste; Rider Mark; Van Schaftingen Emile;
Language
French
Prerequisites
Sbim2115 is a prerequisite
Main themes
This course helps to deepen the knowledge on post-translational modifications of proteins. It is the perfect continuation of wsbim2115.
Content
|
General introduction on the importance of post-translational modifications of proteins in their regulation and function (1h L.Bertrand) - Mechanisms of disulfide bond formation in prokaryotes and eukaryotes (3h J.-F. Collet) - Protein phosphorylations (4h M. Rider) - The new world of other post-translational modifications (Acetylation, O-GlcNacylation) (4h L. Bertrand) - Mechanisms of targeted proteolysis, protein ubiquitination and related post-translational modifications (J.B. Demoulin) - Protein repair mechanisms. (E. Van Schaftingen) |
Teaching methods
The different parts of the course will be given by specialists of the domains using powerpoint slides. The slides will be available for the students.
Evaluation methods
Written exam on all parts of the course
Faculty or entity
SBIM
