wsbim2141  2017-2018  Bruxelles Woluwe

3 credits
30.0 h
Q1
Teacher(s)
Constantinescu Stefan; Decottignies Anabelle; Feron Olivier; Lemaigre Frédéric coordinator; Sonveaux Pierre;
Language
French
Prerequisites
fundamental principles in cell and molecular biology, and in biochemistry (metabolism) taught during the baccalaureate.
Main themes
The course describes the molecular and cell biology of intercellular signaling in normal condition and cancer, the mode of action of anti-cancer drugs, the interaction between tumor cells and their micro-environment, angiogenesis and metabolic anomalies resulting from the adaptation of tumor cells to their micro-environment (hypoxia and acidosis). The course will also address the issue of tumor cell immortality.
Aims

At the end of this learning unit, the student is able to :

1

The course is expected to provide the students with the competence to:

- master the main intercellular signaling pathways, the interactions between tumor cells and blood vessels, the principles of cell immortality and the determinants of tumor cell metabolism;

- understand and explain how perturbed intercellular signaling, abnormal metabolism and cell immortality contribute to to tumor initiation and progression, and metastasis;

- understand and explain how anti-cancer drug modulate intercellular signaling;

- be able to design an experimental approach aiming at the identification of therapeutic targets;

- be able to critically address an oral presentation or article in the field;

- use the acquired knowledge to address knew issues.

 

 

The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.
Content
Other information
The course is taught in auditoria
Slides will be made available to the students.
Bibliography
The biology of Cancer, R.A. Weinberg, Garland Publishing
Faculty or entity
FASB


Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Sigle
Credits
Prerequisites
Aims
Master [120] in Biomedicine

Master [60] in Biomedicine