Teacher(s)

Coulie Pierre coordinator; Lucas Sophie; Renauld Jean-Christophe; Van den Eynde Benoît;

Language

French

Prerequisites

cellular biology, bacteriology, virology, molecular biology, genetics.

The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.

Main themes

Main discoveries that lead to the identification of antibodies, HLA molecules, B and T lymphocytes, and of the main interactions between immune cells, involving or not soluble agents. Description of the main components of innate immunity. Integrated view of all these components at work in infectious diseases, vaccination, autoimmmune diseases, cancer, transplantation and hypersensibility reactions.

Aims

At the end of this learning unit, the student is able to :
1	Understand how our immune system deals with microbes through adaptive and innate immunity. Understand the mechanisms that lead to the two main characteristics of adaptive immunity: specificity and memory. Understand the bases of vaccination, graft rejection responses, autoimmune diseases and hypersensitivity reactions such as allergy.

The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”.

Content

The main concepts are introduced with an historical perspective and the explanation of the principal experimental facts that have led to a major discovery.

Teaching methods

Yearly updated syllabus (2 volumes), slides.

Evaluation methods

written examination with exercices, short answers or essays. No multiple choice.

Faculty or entity

SBIM