Régulations post-traductionnelles des protéines

WSBIM2215  2016-2017  Bruxelles Woluwe

Régulations post-traductionnelles des protéines
2.0 credits
20.0 h
1q

Teacher(s)
Rider Mark ; Bertrand Luc (coordinator) ; Collet Jean-François ; Van Schaftingen Emile ; Demoulin Jean Baptiste ;
Language
Français
Prerequisites

Sbim2115 is a prerequisite

Main themes

This course helps to deepen the knowledge on post-translational modifications of proteins. It is the perfect continuation of wsbim2115.

Evaluation methods

Written exam on all parts of the course

Teaching methods

The different parts of the course will be given by specialists of the domains using powerpoint slides. The slides will be available for the students.

 

Content

General introduction on the importance of post-translational modifications of proteins in their regulation and function (1h L.Bertrand)

-       Mechanisms of disulfide bond formation in prokaryotes and eukaryotes (3h J.-F. Collet)

-   Protein phosphorylations (4h M. Rider) 

- The new world of other post-translational modifications (Acetylation, O-GlcNacylation) (4h L. Bertrand)

-       Mechanisms of targeted proteolysis, protein ubiquitination and related post-translational modifications (J.B. Demoulin)

-       Protein repair mechanisms. (E. Van Schaftingen)

 
Faculty or entity<


Programmes / formations proposant cette unité d'enseignement (UE)

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Aims
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