Régulations post-traductionnelles des protéines [ WSBIM2215 ]
2.0 crédits ECTS
20.0 h
1q
| Teacher(s) |
Bertrand Luc (coordinator) ;
Rider Mark ;
Demoulin Jean Baptiste ;
Van Schaftingen Emile ;
Collet Jean-François ;
|
| Language |
French
|
Place
of the course |
Bruxelles Woluwe
|
| Prerequisites |
Sbim2115 is a prerequisite
|
| Main themes |
This course helps to deepen the knowledge on post-translational modifications of proteins. It is the perfect continuation of wsbim2115.
|
| Aims |
The contribution of this Teaching Unit to the development and
command of the skills and learning outcomes of the programme(s) can be
accessed at the end of this sheet, in the section entitled
“Programmes/courses offering this Teaching Unit”.
|
| Evaluation methods |
Written exam on all parts of the course
|
| Teaching methods |
The different parts of the course will be given by specialists of the domains using powerpoint slides. The slides will be available for the students.
|
| Content |
|
General introduction on the importance of post-translational modifications of proteins in their regulation and function (1h L.Bertrand)
- Mechanisms of disulfide bond formation in prokaryotes and eukaryotes (3h J.-F. Collet)
- Protein phosphorylations (4h M. Rider)
- The new world of other post-translational modifications (Acetylation, O-GlcNacylation) (4h L. Bertrand)
- Mechanisms of targeted proteolysis, protein ubiquitination and related post-translational modifications (J.B. Demoulin)
- Protein repair mechanisms. (E. Van Schaftingen)
|
|
Faculty or entity
in charge |
> SBIM
|
|
|
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