Organic analysis I : separation techniques [ LBIR1318 ]

Icampus

Organic chemistry  CHIM1170

- Properties of chemical compounds

- Strategy of an organic analysis

- Methods for extraction and concentration

- Gas chromatography

- High-pressure liquid chromatography

- Modification of the properties by derivatisation

- Methods of quantification

- Semi-preparative HPLC

- UPLC

- Enantiomeric separations

a. Contribution de l'activité au référentiel AA (AA du programme)

The course contributes to the following learning outcomes : 1, 3 and 6 (BIR program)

b. Formulation spécifique pour cette activité des AA du programme (maximum 10)

At the end of this course, the student will be able to select the best technique to get rid of all major co-constituents, to optimize the resolution of the GC/HPLC chromatograms, to choose the best detector in terms of sensibility and selectivity, to accurately quantify the analytes (use of internal standards, external standards, standard addition, isotopic dilution ..) and to extrapolate the concepts to isolate them by (semi)preparative HPLC or GC.

Written examination for the theoretical part. 3 Oral communications (in English) are presented during the seminars (discussion of experimental protocols). The experimental know-how and the attitude are evaluated throughout practical classes (laboratory report).

Half of the courses consist in magistral lectures, the other part being a reflection (groups of students) around published experimental protocols. The students have also the opportunity to apply a few number of experimental protocols at the laboratory.

- Properties of chemical compounds

- Strategy of an organic analysis

- Methods for extraction and concentration

- Gas chromatography

- High-pressure liquid chromatography

- Modification of the properties by derivatisation

- Methods of quantification

- Semi-preparative HPLC

- UPLC

- Enantiomeric separations

No particular support which would be paying are required.