Chimie organique (3è partie) [ LBIR1317 ]

Icampus

- LCHM1111 'General Chemistry I';

- LCHM1141 'Organic Chemistry I';

- LCHM1211 'General Chemistry II';

- LCHM1241A 'Organic Chemistry II';

- Fundamentals: emphasis on structure and reactivity relationships, acids and bases, carbanions and carbocations, kinetic and thermodynamic considerations of organic reactions.

- Systematic study of reaction mechanism in Organic Chemistry.

- Pericyclic reactions (Woodward-Hoffmann rules) and photochemical reactions.

- Nucleophilic and electrophilic substitution of aromatic compounds: mechanistic investigations

- Oxidation and reduction in Organic Chemistry.

Contribution of the course to the program objectives

B1.1, B1.3, B3.1, B6.2, B7.1

Specific learning outcomes of the course

At the end of the course, the student will be able to:

·      describe the electrons migration within an organic molecule (inductive and conjugation effects) as well as during a chemical reaction between two given compounds

·      establish relations between molecular and spatial structures of organic molecules and some properties, in particular, their reactivity and acidity/basicity ;

·      predict and explain the expected result for the main types of organic reactions, including their mechanism, catalyst  and solvent effect

·      apply theory to everyday life

Students are evaluated through a final oral examination, which includes problem solving, theory and general knowledge of Organic Chemistry.

The course is based on lectures and exercises-based learning.

Chapter I:  Fundamentals: chemical bonds, molecular and supramolecular interactions

Chapter II : Acidity and basicity in Organic Chemistry

Chapter III : Pericyclic reactions and Woodward-Hoffmann rules

Chapter IV : Aromaticity : electrophilic and nucleophilic substitution of aromatic compounds

Chapter V : Oxidation and reduction in Organic Chemistry

The slides presented during the lectures and the exercises are available on i-campus.

Recommended reference books:

- Organic Chemistry (Clayden, Greeves, Warren and Wothers - De Boeck)

- Chimie Organique : généralités, études des grandes fonctions et méthodes spectroscopiques (Rabasso - De Boeck)

- Organic Chemistry (P.Y. Bruice - Pierson International Edition)