Physicochemical studies of pharmaceutical forms [ WFARM2505 ]
3.0 crédits ECTS
20.0 h + 10.0 h
| Teacher(s) |
Vanbever Rita (coordinator) ;
Préat Véronique ;
|
| Language |
French
|
Place
of the course |
Bruxelles Woluwe
|
| Main themes |
Main themes :
1. Analysis of the solid state :
Polymorphism and drug activity
Cristallography and X rays in chemical analysis
Methods of powder analysis :
Particle size
Powder density
Pulmonary deposition of aerosols in vitro
Surface analysis by X-ray photoelectron spectroscopy
Differential scanning calorimetry
2. Analysis of solutions :
Automatic determination of solubility and turbidimetry
3. Analysis of disperse systems :
Liquid interfaces :
Measurement of surface tension
Langmuir balance
Measurement of a CMC
Measurement of the stability of an emulsion
Inclusion complexes
Solid interfaces :
Wetting of solids and measurement of the contact angle
Measurement of the Zeta potential
Solid dispersions
|
| Aims |
To thoroughly study methods for physicochemical analysis of pharmaceutical formulations
|
| Content |
Method :
Theoretical course completed with an experimental work : measurement of solid cristallinity, measurement of particle size, measurement of powder density, measurement of the pulmonary deposition of aerosols in vitro, measurement of the Zeta potential.
|
| Other information |
Prerequisite : FARM 1307 "Physical pharmacy"
Evaluation :
Oral or written examen (to be determined with the students), evaluation of the experimental work
|
Cycle et année
d'étude |
> Master [120] in Pharmacy
|
Faculty or entity
in charge |
> FARM
|
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