Molecular genetics and drugs [ WFARM1382 ]
2.0 crédits ECTS
30.0 h
2q
| Teacher(s) |
De Plaen Etienne ;
Octave Jean-Noël (coordinator) ;
|
| Language |
French
|
Place
of the course |
Bruxelles Woluwe
|
| Main themes |
Cloning and expression in prokaryotic and eukaryotic cells. Genetic engineering and production of proteins that are useful in biomedical and pharmaceutical sciences. Utilization of DNA polymorphisms as diagnostic tools. Transgenic animals. DNA modifications in hereditary diseases. Gene therapy.
|
| Aims |
The objectives are to learn the approaches of molecular biology, which allow the analysis of DNA and RNA to develop both diagnostic tools as well as cellular and animal models needed in biomedical and pharmaceutical sciences.
|
| Content |
Description and utilization of different cloning and expression vectors in procaryotic cells. Construction and screening of genomic DNA libraries. Analysis of the DNA molecule : Detection of different polymorphisms. Construction and screening of cDNA libraries. Cloning and expression of cDNA in different cell types. Overexpression and knock out of genes in transgenic animals. Examples of gene therapy.
|
| Other information |
Assessment: By written exam.
Support: Notes and Power Point presentations provided by the lecturers.
|
Cycle et année
d'étude |
> Bachelor in Pharmacy
> Bachelor in Biomedicine
> Preparatory year for Master in Biomedicine
|
Faculty or entity
in charge |
> FARM
|
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