UCL - Radiochemistry, radiotoxicology et radiopharmacy

[RFAR2100]

[22.5h + 60h] 4 credits

Teacher(s): Bernard Gallez

Language: French

Level: Second

Aims
Main themes
Content and teaching methods

Aims

This course is intended for (future) professionals with professional activities dealing with the use of non sealed radioactive sources. 3 areas are covered: radiotoxicology (with focus on internal contaminations, their diagnosis, and their treatments); radiochemistry (with focus on nuclear reactions and nuclear chemistry for the preparation of radiolabeled compounds for medical use); radiopharmacy (quality control and quality assurance, special problems with some radiopharmaceuticals)

Main themes

I. Lecture
Elements of nuclear physics for the applications in radiopharmacy
Radiotoxicology
Radiochemistry
Radiopharmacy
II. Practical exercises

Counting statistics
Attenuation
Protein labeling, purification, radiochemical purity
Liquid scintillation : chemiluminescence, quenching
Blood volume determination
Quality control of generator 99Mo/99m Tc eluate
Quality control of HMPAO-Tc
Biological distribution

III. SEMINARS
Personnalized work for the student in the area of his specialization

Content and teaching methods

Lectures: 2 hours blocks on a special topic
Practical exercise: 1 week with handling of radioactive materials (labelling, quality control)
Seminars: Personnalized work for the student in the area of his specialization