Complements of organic chemistry
[MAPR1230]
[15h + 15h] 3 credits
This course is taught in the 1st semester.
Teacher(s): Sophie Demoustier, Pierre Godard(coord.)
Language: French
Level: First
Aims
to initiate the students to a logical thinking based on some experimental observations and susceptible of generalization.
At the end of the module, the students would be able
to emphasize the relationships between molecular and spatial structures and some properties, more particularly their behaviour as organic reactant.
to understand, on the base of the electron displacements inside molecules, the mechanisms of the different steps intervening in the main organic reactions.
Main themes
The first part (0.2 ECTS) deals with the structures and bonds in organic molecules
The second part (0.5 ECTS) is devoted to the study of the influence of the electronic structure of organic molecules on some physical properties.
The third part (1.8 ECTS) develops the main reactions in organic chemistry.
Content and teaching methods
Part 1 :
Covalent bonds, concept of hybridisation and geometry
Functions and functional groups, functionality
Concept of isomerism including stereo isomerism
Part 2 : Electron displacements inside molecules
Inductive effects (permanent polarization) and polarizability (induced polarization)
Mesomer effect
Relations with some properties (boiling temperature, acid-base character, acid and base strength)
Part 3 : Reactivity from some examples choosen between following reactions:
Nucleophilic substitution reactions on aliphatic carbon
Electrophilic and radical addition reactions on alkenes
Elimination reactions of alkyl halides and alcohols
Addition and substitution reactions on carbonyl compounds
Substitution on aromatic compounds
Oxidation and reduction reactions
Methods :
Ex-cathedra courses and exercises, eventually study developed from problems.
Some laboratories would be indicated but are not organized at the present time.
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)