UCL - Further development in analytical toxicology and phytopharmacy

[FARM2502]

[20h + 10h] 3 credits

This course is taught in the 2d semester.

Teacher(s): Pierre Wallemacq

Language: French

Level: Second

Aims
Main themes
Content and teaching methods
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Aims

This lecture aims to provide students the necessary understanding of the analytical, kinetics, and metabolic basis of the major intoxications found in clinical setting. At the end of this lecture, students should be able to discriminate potentially lethal intoxications, to propose analytical tools to detect toxics in biological fluids and to interpret analytical results in a medical context. The 10h of practical exercises are only proposed to specialized pharmacists in training in clinical biology (Master complementary)

Main themes

Analytical methods used in clinical toxicology
Biological matrices
Toxicokinetics
Major intoxications (alcohols, CO, psychotropic drugs, drugs of abuse, sedatives)
Pesticides
Mushrooms

Content and teaching methods

This lecture starts by a detailed review of the analytical methods available in clinical toxicology (immunoassays, chromatography including mass-spectrometric detection,), together with basis of toxicokinetics. Major families of toxics are reviewed, and include solvants, CO, drugs of abuse, psychotropes, antidepressive drugs, sedatives with some epidemiological, analytical, metabolic and clinical interpretation approaches. Practical exercises are offered to specialized pharmacists in clinical biology.

Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Evaluation : written exam
Support : Slides on I-campus