UCL - Pharmacogenomics basis

[FACL2102]

[15h] 2 credits

Teacher(s): Vincent Haufroid

Language: French

Level: Second

Aims
Main themes
Content and teaching methods
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Aims

To understand the variability of human genome, its polymorphisms, their frequencies and evolution (genomics) and the importance of genetic variations for pharmacological treatments.

Main themes

Genomics basis
Clinical applications of pharmacogenomics

Content and teaching methods

The formation will include genomics basis including a review of analytical techniques for the detection of genetic variants and the measure of gene expression differences. The main part of the formation will focus on the influence of genetic polymorphisms on the clinical response (therapeutic efficacy + adverse drug reaction) after drug administration. Future perspectives in term of personalized medicine will be also presented.

Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Pre-requisite : General and special pharmacology
Evaluation : written examination and personalized work (presentation of a topic in the field of pharmacogenomics).