UCL - Research in Surgery

[CHG2010]

[15h] 2 credits

This course is taught in the 1st semester.

Teacher(s): Xavier Banse, Xavier Banse, Denis Dufrane(coord.), Alex Kartheuser, Jean-Marie Maloteaux, Michel Mourad, Alain PONCELET, Bertrand Tombal

Language: French

Level: Second

Aims
Main themes
Content and teaching methods
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Aims

CHG2010 course will be associated to the "Seminar of Transplantation CGH2250" and will investigate the development of cellular therapy and tissue engineering in transplantation.

Main themes

The course of experimental Surgery is based on 3 main topics :

Axe 1: Establishment of an experimental research protocol in surgery: (i) Development of an experimental hypothesis from a specific hurdle in surgery. (ii) Learning of specific research in scientific literature. (iii) In vivo approach for small animal (in rat and mice) and pre-clinical (primates and pigs) models: Legislation, Ethics, Advantages and Limits of these models. (iv) Study of in vitro testing (cellular contact, biocompatibility,...) to avoid in vivo testing. (v) Approach of statistical analysis for results.

Axe 2: Field of research in modern surgery : Cellular and tissular Bioengineering (artificial organs and tissues), surgical robotic, cellular transplantation, xenotransplantation, stem cells, cellular regeneration. Approach of biomaterials used in surgery.

Axe 3: Translation: Laboratory to clinical application: Approach of clinical phases required for the utilisation of new therapeutic tools in surgery: Legislation and Ethics.

Content and teaching methods

Methodology for research in modern surgery.

Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)

Evaluation: The CHG2010 will be assessed by an oral examination: analyse of the objectivity of scientific study (analyse of Materials and Methods, Results) for potential application in surgery.