Biomaterials
[GBIO2030]
[30h + 30h] 5 credits
This course is taught in the 2d semester.
Teacher(s):
Language: French
Level: Second
Aims
Introductory course to biomaterials science.
Upon completion of this course, the students will be able to:
1. Describe the structure and properties of the different classes of biomaterials;
2. Describe the principles driving the interactions between materials and living organisms;
3. Justify the choice of a given biomaterial according to the function that it has to fulfill when exposed to a biological system or implanted into a human body.
Main themes
The course is divided into 3 parts. The first part is a general introduction to the main classes of biomaterials: structure of natural and synthetic materials (polymers, ceramics and glasses, metals and composite materials); the second part approaches biomaterials properties: mechanic properties, surface properties compared with mass properties, physical and chemical properties, degradability. This part implies the study of the interactions between materials and living organisms: protein adsorption, cell adhesion, inflammation, immunitary reaction, coagulation, ; the third part will include a range of selected application examples of the different classes of biomaterials in medicine, biology and artificial organs : cardiovascular biomaterials, orthopedic biomaterials, dental materials, materials specific to drug delivery, biosensors, tissues engineering,
Content and teaching methods
Part 1 : General introduction to the main classes of biomaterials
1.1 Polymers
1.2 Metals
1.3 Ceramics
1.4 Composite materials
1.5. Hydrogels
1.6. Natural materials
Part 2 : Properties of biomaterials
2.1. Mechanical properties
2.2. Surface properties vs. mass properties
2.3. Interaction biomaterials-living organisms
Part 3 : Biomaterials Applications in medicine + selected examples
Method :
Theoretical course (30h) + Practical work (30h).
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)
Prerequisite: basic notions in chemistry, biochemistry, physics and materials science.