Introduction to genetics
[BIO1221]
[25h + 15h] 3 credits
This course is taught in the 2d semester.
Teacher(s): André Lejeune
Language: French
Level: First
Aims
- To know and understand the mechanisms ruling the transmission of genes from one generation to the next and the genetic variations that occur in populations;
- To solve exercises relevant to the themes mentioned above.
Main themes
The study of genetics is envisioned at two levels of organisation of the living world. At the level of individuals, general laws of transmission of genes, their application to certain particular cases and exceptions will be exposed. Connections with certain aspects of metabolism and a brief overview of genomic notions will be presented. At the level of populations, we study variations of genetic characteristics and connect them with certain aspects of evolution.
Content and teaching methods
1. Genetics and the organism
2. Classical genetics. 2.1 Patterns of inheritance (laws of Mendel). 2.2 Chromosomal basis of heredity. 2.3 Extensions of Mendelian heredity (incomplete dominance, codominance, lethal alleles, multiple alleles, gene interactions). 2.4 Gene linkage and genetic mapping
3. Overview of genomics
4. Population genetics. 3.1 Hardy-Weinberg equilibrium. 3.2 Variations in populations.
Method
Theoretical classes and exercises. Debate on a selected topic linking genetics and society.
Other information (prerequisite, evaluation (assessment methods), course materials recommended readings, ...)
Evaluation : written examination on theory and exercises
Written support : books, overhead transparencies, portfolio of reading material.