Rare. Eosinophilic cellulitis of unknown pathogenesis.

It combines the clinical appearance of

-        pruritic dermo-hypodermatitis: erythematous plaques which may be urticarial, nodular, papulo-nodular, or very rarely vesiculobullous 

-        frequent hyper eosinophilia in the blood,

-        suggestive histological images: in early inflammatory lesions, a dermal infiltrate of eosinophils is found in the dermis, followed later by a "flaming" image of collagen fibers and eosinophilic debris.

There are many possible causes: infection, arthropod bite, vaccination, haemopathy, malignancy, chronic inflammatory bowel disease or medication. Many cases are idiopathic.

Treatment: topical or systemic corticosteroid therapy, antihistamines for pruritus.

Anesthetic implications:

corticotherapy

References : 

-        Shimshak S, Wentworth A, Sokumbi O.
Edematous plaque on the elbow of an infant.
J Pediatr 2023;262:113661

Updated: December 2023