TORCH complex or syndrome
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(TORCHES)
Severe embryofetopathy. Acronym for Toxoplasmosis, Other infections, Rubella, Cytomegalovirus and Herpes simplex. The other possible infections: Coxsackie, syphilis, HIV, parvovirus B19 and herpes zoster (chickenpox). Sometimes the acronym TORCHES for TOxoplasmose, Rubella, Cytomegalovirus, Herpes simplex and Syphylis is preferred.
Group of pre- or perinatal infections of viral, bacterial or Protozoan origin that have similar symptoms:
- microcephaly
- intracerebral calcifications
- chorioretinitis
- and affecting other organs, according to the involved germ: thrombocytopenia, congenital cataract...
At birth, there is often an intrauterine growth retardation, a hepato-splenomegaly and sometimes a jaundice and a petechial rash.
Anesthetic implications:
mental retardation, epilepsy; management of a polyhandicapped child; check liver function
References :
Updated: September 2018