[MIM 600 705]

Multisystemic disease probably of autoimmune origin. Onset in childhood and female predominance.

It combines:

-        muscle spasms and myalgias

-        alopecia

-        chronic diarrhea: malnutrition, weight loss, iron deficiency anemia, hypoproteinemia

-        osseous problems probably secondary to muscle spasms: osteolysis, stress fractures, epiphysiolyses, bone lesions at tendon insertion sites, early osteoarthritis

-        growth retardation

-        primary amenorrhea.

Endoscopy: alterations of the mucous membranes that appear granular or ulcerated (lymphoplasmocytic infiltrate), presence of small cystic lesions in the gastric mucosa (gastritis cystica polyposa)

Anesthetic implications:

check blood count and protein levels; side effects of current treatments (corticosteroids, immunosuppression)

References :

-        Solis Garcia del Poso J, de Cabo C, Solera J.
Gastrointestinal manifestations in Satayoshi syndrome: a systematic review.
Orphanet J Rare Diseases 2020 ; 15 :115

Updated: June 2020