[MIM 258 040]

Acronym for Omphalocele, cloacal Exstrophy, Imperforate anus and Spinal defects.

The prevalence is estimated at 1/200,000 to 1/400,000 pregnancies. Sporadic. Association of anomalies of the median line of the lower part of the body.

Presence of:

-         an omphalocele

-           a bladder or cloacal extrophy

-           an imperforate anus

-         vertebral and often central nervous system anomalies

Anesthetic implications:

complex neonatal surgery

References :

-        Keppler-Noreuil, K. M. 
OEIS complex (omphalocele-exstrophy-imperforate anus-spinal defects): a review of 14 cases. 
Am J Med Genet 2001, 99: 271-9.

-        Wong TLW, Baki MM, Ishak S, See GB.
A bizarre case of accessory larynx in an infant with OEIS syndrome.
Int J Pediatr Otorhinolaryngol Extra 2018 ; 114 : 143-7

Updated: November 2018