Miller-Fisher, syndrome
|
Rare. Autoimmune neurological disorder of infectious origin (gastroenteritis) close to Guillain-Barre syndrome. Characterized by: sensory ataxia, ophthalmoplegia, generalized areflexia. Muscle weakness may progress to complete paralysis with respiratory failure.
In general, recovery in less than 6 months. Presence of anti-Gq1b (myelin) antibodies. Recurrence is rare (< 3 %).
Treatment: IV gammaglobulins, plasmapheresis.
Anesthetic implications:
muscle weakness, risk of aspiration pneumonitis if the bulb is affected
References :
Updated: December 2018