[MIM 137 280]

(giant hypertrophic gastropathy)

Rare. Acquired pathology of the gastric mucosa the folds of which get hypertrophic (especially at the level of the fundus) resulting in a massive loss of protein secondary to hypersecretion of gastric mucus. At histologyicalexamination: thickening of the mucosa, foveolar hyperplasia and glandular atrophy .

Signs: epigastric pain, vomiting, hypoalbuminemia, weight loss.

Sometimes associated with Helicobacter pilori or CMV infection.

In adults, associated with lymphocytic gastritis or gastric carcinoma (10-15%).

Anesthetic implications:

check plasmatic protein level; important gastric volume of fluids.

References:

-        Bontems P, Gottrand F.
Gastrites, duodénites, ulcères gastriques et duodénaux,
in Gastroentérologie clinique, coordonné par F Gottrand et D Turck, Doin 2016, p 67-78.

-        Akita C, Saikawa Y.
Gastric gyri : pediatric Ménétrier’s disease.
NEJM 2017; 376: 774

Updated: March 2017