Incidence: 1.106. Dermatosis that usually appears during childhood or adolescence (about 14 years of median age) as hyperpigmented  (brownish), slightly atrophic, unilateral lesions organized in bands corresponding to the Blaschko's lines on the trunk and limbs (some cases of isolated facial localization have been described). The disease is non-progressive. There is no inflammatory episode prior to the onset of the lesions, nor is there any subsequent scleroderma. The etiology remains unknown but, since the eruption follows the Blaschko's lines, it could be due to a mosaicism of a post-zygotic mutation of a susceptibility gene.

Differential diagnosis: linear scleroderma (see this term) and Pasini and Pierini atrophoderma, which does not follow the Blaschko's lines.

Histology: pigmentary overload in the epidermal basal cells, abnormal collagen fibers in the dermis.

Treatment: early topical applications of calcipotriol could possibly decrease the pigmentation of the lesions.

Anesthetic implications:

none

References:

-         Fleuret C, Kupfer-Bessaguet I, Staroz F, Plantin P.
Atrophodermie linéaire de Moulin : à propos de 3 cas.
Ann Dermatol Vénéréol  2013 ; 140 : P243

-        Wang W-M, Zeng Y-P.
Linear atrophoderma of Moulin.
JAMA Dermatology E1, online April 1 2020

Updated: April 2020