Lane-Hamilton, syndrome
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Very rare. Association of idiopathic pulmonary hemosiderosis and celiac disease (see this topic).
Diagnostic elements:
- iron deficiency anemia
- lung symptoms: chronic cough, episodes of shortness of breath, hemoptoic sputum
- infiltrates or a miliary picture on chest XRay
Retinitis pigmentosa is frequently associated. The cause of the condition is probably autoimmune as a gluten-free diet corrects all the anomalies.
Anesthetic implications:
check hemoglobin levels; chest XRay; SpO2 at room air
References :
- Hendrickx GFM. Somers K, Vandenplas Y.
Lane-Hamilton syndrome :case report and review of the literature.
Eur J Pediatr 2011; 170:1597-1602
- Paksu S, Paksu MS, Kalayci AG, Sancak R.
Lane-Hamilton syndrome: association or coincidence?
Indian Pediatrics 2013; 49: 243-4
- Villegas VM, Rachitskaya AV, Lam BL, McKeown CA, Berrocal AM.
An unusual ophthalmic finding in Lane-Hamilton syndrome.
J of AAPOS 2014; 14: 617.
Updated: February 2019