See also thalassemias

Rare. More frequent in people originating from the Mediterranean countries. Abnormal hemoglobin that results from the fusion of the δ and β genes of globin by imperfect crossover  of two chromosomes leading to the formation a gene δβ. The most  frequent hemoglobin Lepore is called hemoglobin Boston. The term anti-Lepore hemoglobin or Miyada is used when the sequence of fused genes is reversed ßδ.

The result is a deficit of synthesis of the β chain and a clinical picture similar to β-thalassemia with sometimes a heterozygotic status composed of β thal/Lepore.

Anesthetic implications: 

complete blood count, platelets count, bilirubinemia

References : 

Updated: March 2019