Evans, syndrome
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(Autoimmune pancytopenia)
Very rare. Chronic hematological pathology that associates, simultaneously or sequentially, an immune thrombocytopenic purpura and an hemolytic anemia with a positive Coombs test. Neutropenia is sometimes associated.
Treatment:
1) corticosteroids, immunoglobulin
2) immunosuppression or rituximab
3) bone marrow transplantation in case of failure of the other treatments.
Anesthetic implications:
check complete blood count; side effects of the treatments: immunization, iron overload, etc...
References :
Updated: June 2019