Carrington, disease
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(Chronic eosinophilic pneumonia)
Very rare. Association of respiratory and general subacute or chronic symptoms caused by an alveolar and/or plasmatic eosinophilia and peripheral lung infiltrates at imagery. Blood eosinophils level is generally greater than 1,000 / mm3. The response to oral corticosteroid therapy is spectacular, and may constitute a test diagnosis for the disease. However, relapse or evolution to a severe asthma are frequent when the dose is reduced or the treatment discontinued.
In some cases, an evolution to Churg-Strauss syndrome (see this term) is observed.
Anesthetic implications:
check arterial blood gases at room air; a bronchodilator or chronic corticoids are usually taken by the patient.
References :
- Marchand E, Cordier JF.
Pneumopathie chronique idiopathique à éosinophiles.
Rev Mal Respir 2006 ; 23 : 13S : 99-108.
Updated: June 2019