Cantù, syndrome

Rare. Autosomal dominant transmission or sporadic. Association of osteochondrodysplasia (dwarfism), hypertrichosis and cardiomegaly. Macrosomy at birth. Cardiomegaly with narrow chest and broad ribs: bicuspid aortic valve, pulmonary hypertension, biventricular hypertrophy and recurring pericardial effusion. Coarse aspect (as in overload diseases) with macroglossia; sometimes microcephaly and alopecia.

Deep palmar  and plantar skin creases. Platyspondyly with a wide spinal canal; hypoplasia of the hips with coxa vara, osteopenia.


Anesthetic implications: 

preoperative echocardiography. Risk of difficult intubation/mask ventilation .


References : 

O’Brien JJ, Ririe DG. 

Anesthetic experience in a patient with Cantù syndrome. 

Pediatr Anesth 2008, 18 : 1255-7.


Updated: November 2019