Alice in Wonderland syndrome
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(Todd syndrome)
Neurologic disorder that modifies the perception of space, time and oneself.
The patient may present with:
- micropsia: objects are perceived smaller than they are in reality
- macropsia: objects appear bigger than they are, causing the person to feel smaller than they actually are
- teleopsia: objects appear much further than they actually are
- pelopsia objects appear closer than they actually are
- metamorphopsia: objects are transformed (e.g. distortion)
- alteration of the notion of time or colors
The main cause of this syndrome is migraine (see this term), specifically in children. Another cause is an Epstein-Barr virus (EBV) or herpes virus 4 (HHV-4) infection. These disorders of dissociation may also appear in some forms of epilepsy, intoxication (LSD), episodes of stress or post-traumatic stress yndrome
Anesthetic implications:
longterm migraine treatment must be continued
References :
- O’Toole P, Modestino EJ.
Alice in Wonderland syndrome : a real life version of Lewis Carroll’s novel.
Brain & Development 2017 ; 39 : 470-4
Updated: December 2018