Dynamic analysis of chemical and biochemical reaction networks

Antonio Alonso, IMM-CSIC, Vigo, Spain

The objective of this course is to review state of the art theory and methods dedicated to the analysis of chemical and biochemical network dynamics. In particular, emphasis will be put on the role of the network structure and parameters on the class of dynamic behaviour exhibited.

To this end, the framework of CRNT (Chemical Reaction Network Theory) as developed by M. Feinberg and co-workers will be revisited and adapted to set up links with alternative approaches as well as to establish connections with the underlying physical reaction kinetic principles.

The course will comprise 4 lectures:

Monday 22 November (10:30-12:30): "General motivation in the context of biochemical systems"

Monday 22 November (14:00-17:00): "Formal representation of reaction networks and critical discussion of the essential results of CRNT with particular emphasis on the concept of network deficiency"

Wednesday 24 November (10:30-12:30): "Effect of parameters on the nature of possible equilibrium points in a geometric context"

Wednesday 24 November (14:00-17:00): "Numerical methods to compute parameter regions associated to multistability"

Conclusion of the course with a personal view of open problems and perhaps promising solutions.

Practical information :

Place : Automation Department seminar room, Mons Faculty of Engineering
Registration : Mrs Véronique Piette


Doctoral course : 6 lectures in multicriteria decision aid and multi-objective optimization

Organizers: Y. De Smet (ULB), Th. Marchant (UGent), M. Pirlot (UMONS)

Target audience: doctoral students in decision, optimization, operational research, preferences in data base search.

Goal: offer an introduction (at doctoral level) to a few fundamental mathematical models in the field of multiple criteria decision analysis and multi-objective optimization and to algorithmic problems raised by the use of such models.

Organization: six lectures of about 3 hours in English (once a month from January to June, 2011). Each lecture focuses on a specific topic. All lectures will take place in Brussels (ULB, Campus Plaine) or Mons (UMONS, Faculté Polytechnique) as indicated in the programme below.

Venue for the first lecture in Mons: UMONS, Faculté Polytechnique, rue de Houdain 9, 7000 Mons, Seminar room of MathRO (Mathematics and Operational Research department), third floor.

All lectures in Mons will take place in the same room.

The location of the lectures in Brussels will be announced later.

For further information: Prof. Marc Pirlot, marc.pirlot@umons.ac.be.

Inscription is free; for organizational purposes it is asked that people intending to attend the lectures let it know to one of the organizers.

Programme

1. January 20, 2011 (Thursday), 14.00-17.00 in Mons - M. Pirlot (UMONS): Additive value functions and conjoint measurement

2. February 23, 2011 (Wednesday), 14.00-17.00 in Brussels - D. Bouyssou (CNRS Paris Dauphine): Models for deciding under risk and uncertainty

3. March 23, 2011 (Wednesday), 14.00-17.00 in Brussels - J. Figueira (Université de Nancy): Outranking methods

4. April 27, 2011 (Wednesday), 14.00-17.00 in Mons - P. Meyer (Telecom Bretagne): Algorithms and software for aiding decision : the Decision Deck project

5. May 18, 2011 (Wednesday), 14.00-17.00 in Brussels - (To be confirmed) M. Geiger (Universität Hamburg): Interactive methods in multiple objective optimization

6. June 15, 2011 (Wednesday), 14.00-17.00 in Mons - P. Perny (Paris VI): Multiobjective combinatorial optimization

This programme could be modified. The persons who would like to be informed of possible changes in the programme are invited to contact the organizers.

This course is organized with the support of the thematic doctoral school in Mathematics.


ELEC Spring School 2011

Within the department ELEC of the VUB (http://wwwtw.vub.ac.be/elec/), we organize the 4th edition of a 4 weeks spring school (from Monday 9th of May 2011 till Friday the 3th of June 2011) to give an intensive training on advanced modelling and simulation techniques of (non)linear dynamic systems, starting from experimental data.

Besides classical courses and exercises, we also provide hands-on experience by working on small projects that can be defined depending on your personal interest. The participants should have a good basic knowledge in system theory and signal processing. The course covers the following topics:

  • A basic introduction to system identification;
  • Measuring dynamic systems;
  • Identification of dynamic systems;
  • Measuring and modeling of nonlinear systems;
  • Simulation tools for nonlinear systems;
  • Nonlinear distortion analysis in microwave and integrated circuits and systems.

The maximum number of participants will be restricted to 15 researchers.

Participation to this workshop offers a number of advantages. Besides the training, it can also be the start of a collaboration. To some of the participants we can offer a one year grant to start a research collaboration, or even a full four years grant for a (joint) PhD.

Interested candidates are invited to send their curriculum vitae, together with a short motivation why they would like to follow this course, and this before the 16th of January 2011. They can also express their interest in the possibility for a longer cooperation. Please do not hesitate to contact us if you would like to have more information: ldelocht@vub.ac.be or johan.schoukens@vub.ac.be

General information

Within the department ELEC (http://wwwtw.vub.ac.be/elec/) we created a Centre for Data Based Modelling and Model Quality Assessment. The goal of this project is to develop, acquire, and disseminate methods to build models from experimental data.

This project follows different lines towards this long term goal:

  • Development of advanced identification methods for dynamic systems, including high risk new challenges.
  • Learning, dissemination, networking : the aim is to acquire and disseminate actively knowledge from/to other fields by offering training grants and one year research grants for visitors who want to learn how system identification methods can be used in their research project.

The 4 weeks doctoral school fits in the second activity.

Download the courses description.


Course at the University of Namur (FUNDP)

During the second half of this academic year (6, 8, 27 and 29 April and 4, 6, 11 and 13 May 2011) a course entitled Dynamical modelling, estimation and control of reaction systems will be given at the University of Namur (FUNDP) by Professor Denis Dochain (Université Catholique de Louvain, École Polytechnique de Louvain, Institut ICTEAM)

The aim of this course is to introduce the attendees to the paramount concepts of dynamical systems in which matter and energy transformations are involved, for example chemical, biological and ecological systems, their mathematical properties and the use of the latters for developping appropriate and efficient tools of monitoring and control.

The main topics that will be developed in the course are the following :

  • Dynamical models of reaction systems
  • Properties of reaction system models
  • Design of monitoring tools (state and parameter estimation)
  • Design of control laws

References :

  • Dochain D., Automatique des Bioprocédés, Hermès, Paris, 2001.
  • Bastin G. and Dochain D., On-line Estimation and Adaptive Control of Bioreactors, Elsevier, Amsterdam, 1990.

The course will be given in French at the Departement of Mathematics of the University of Namur (FUNDP), 2nd floor of the Economic Sciences building, rempart de la vierge 8, Namur, room MA 2. The lectures will take place from 9:00 am to 12:30 at the following dates: 6, 8, 27 and 29 April and 4, 6, 11 and 13 May 2011.

Those who are interested in attending the course are invited to send an email to Joseph Winkin before 5 April.